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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
|
J Bacteriol. 1993;175(21):6881-9.
Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.
Best EA, Knauf VC.
(
7693652
)
|
|
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Deletion
|
OCR33,35-4 (AK4-2 / BK5-2)
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
accA
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Related strains
|
|
Strains Search
|
Search strains by gene name:
accA
Search strains by all related name:
accA b0185 ECK0184 JW0180
|
General information (Go to Linear View: )
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Gene Name
|
accA
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Alternative name
|
b0185,ECK0184,JW0180
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Location, Length
|
208,621 - 209,580
(
+
)
;
4.50
min
;
960
(bp) ,
319
(aa)
|
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Product
|
acetyl-CoA carboxylase, carboxytransferase, alpha subunit
|
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Operon Name
|
accA
|
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Note
|
acetylCoA carboxylase, carboxytransferase component, alpha subunit; GO_component: GO:0005737 - cytoplasm
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Function
|
enzyme; Fatty acid and phosphatidic acid biosynthesis
|
|
Gene Ontology
|
GO:0003989
;
acetyl-CoA carboxylase activity ( accA )
GO:0005515
;
protein binding ( accA )
GO:0005737
;
cytoplasm ( accA )
GO:0006633
;
fatty acid biosynthetic process ( accA )
GO:0008610
;
lipid biosynthetic process ( accA )
GO:0009317
;
acetyl-CoA carboxylase complex ( accA )
GO:0016874
;
ligase activity ( accA )
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PID
|
1786382
|
EC number
(KEGG Pathway)
|
6.4.1.2
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
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EcoGene
|
accA
(
EG11647
)
|
|
Number of removed
|
1 aa cleaved
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
ACCA_ECOLI
(
P30867
)
|
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- Protein name
|
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha
|
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- Synonyms
|
EC 6.4.1.2
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- Gene name
|
Name=accA; OrderedLocusNames=b0185, z0197, ECs0187, SF0175, S0178;
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MMBR References
|
J Biol Chem. 1992;267:16841-16847
The genes encoding the two carboxyltransferase subunits of Escherichia coli acetyl-CoA carboxylase.
Li, S. J., and J. E. Cronan, Jr.
|
J Bacteriol. 1993;175:332-340
Growth rate regulation of Escherichia coli acetyl coenzyme A carboxylase, which catalyzes the first committed step of lipid biosynthesis.
Li, S.-J., and J. E. Cronan, Jr.
|
| Sequences |
Amino acid
FASTA format
|
0001 MSLNFLDFEQ PIAELEAKID SLTAVSRQDE KLDINIDEEV HRLREKSVEL TRKIFADLGA WQIAQLARHP
0071 QRPYTLDYVR LAFDEFDELA GDRAYADDKA IVGGIARLDG RPVMIIGHQK GRETKEKIRR NFGMPAPEGY
0141 RKALRLMQMA ERFKMPIITF IDTPGAYPGV GAEERGQSEA IARNLREMSR LGVPVVCTVI GEGGSGGALA
0211 IGVGDKVNML QYSTYSVISP EGCASILWKS ADKAPLAAEA MGIIAPRLKE LKLIDSIIPE PLGGAHRNPE
0281 AMAASLKAQL LADLADLDVL STEDLKNRRY QRLMSYGYA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GACGTGGCGT GTCTCTCCGA GCGATCGTTT
-070 ATTAAACGAT CTCCGTGGCC TCATTGGTTC GGAGCAGGTG GAACTGGAGT TTGACTAATA CAGGAATACT
0001 atgagtctga atttccttga ttttgaacag ccgattgcag agctggaagc gaaaatcgat tctctgactg
0071 cggttagccg tcaggatgag aaactggata ttaacatcga tgaagaagtg catcgtctgc gtgaaaaaag
0141 cgtagaactg acacgtaaaa tcttcgccga tctcggtgca tggcagattg cgcaactggc acgccatcca
0211 cagcgtcctt ataccctgga ttacgttcgc ctggcatttg atgaatttga cgaactggct ggcgaccgcg
0281 cgtatgcaga cgataaagct atcgtcggtg gtatcgcccg tctcgatggt cgtccggtga tgatcattgg
0351 tcatcaaaaa ggtcgtgaaa ccaaagaaaa aattcgccgt aactttggta tgccagcgcc agaaggttac
0421 cgcaaagcac tgcgtctgat gcaaatggct gaacgcttta agatgcctat catcaccttt atcgacaccc
0491 cgggggctta tcctggcgtg ggcgcagaag agcgtggtca gtctgaagcc attgcacgca acctgcgtga
0561 aatgtctcgc ctcggcgtac cggtagtttg tacggttatc ggtgaaggtg gttctggcgg tgcgctggcg
0631 attggcgtgg gcgataaagt gaatatgctg caatacagca cctattccgt tatctcgccg gaaggttgtg
0701 cgtccattct gtggaagagc gccgacaaag cgccgctggc ggctgaagcg atgggtatca ttgctccgcg
0771 tctgaaagaa ctgaaactga tcgactccat catcccggaa ccactgggtg gtgctcaccg taacccggaa
0841 gcgatggcgg catcgttgaa agcgcaactg ctggcggatc tggccgatct cgacgtgtta agcactgaag
0911 atttaaaaaa tcgtcgttat cagcgcctga tgagctacgg ttacgcgtaa TTCGCAAAAG TTCTGAAAAA
0981 GGGTCACTTC GGTGGCCCTT TTTTATCGCC ACGGTTTGAG CAGGCTATGA TTAAGGAAGG ATTTTCCAGG
1051 AGGAACACAT
|
