MG1655
W3110
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Gene Report : fixX
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Basic Microbiol. 1995;35(4):217-27.
The fix Escherichia coli region contains four genes related to carnitine metabolism.
Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
     Deletion OCR28 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fixX
Related strains
     Strains Search Search strains by gene name:  fixX   Search strains by all related name:  fixX b0044 ECK0045 JW0043 yaaT

General information  (Go to Linear View:)
 Gene Name fixX  
 Alternative name b0044,ECK0045,JW0043,yaaT  
 Location, Length 45,463 - 45,750 (  +  ) ;   0.98 min ; 288 (bp) ,   95 (aa) Go to Linear View
 Product putative 4Fe-4S ferredoxin-type protein  
 Operon Name fixABCX  
 Note putative ferredoxin; GO_process: GO:0042413 - carnitine catabolic process  
 Function putative carrier; Not classified  
 Gene Ontology GO:0005506 ; iron ion binding ( fixX )
GO:0006118 ; electron transport ( fixX )
GO:0006810 ; transport ( fixX )
GO:0046872 ; metal ion binding ( fixX )
GO:0051536 ; iron-sulfur cluster binding ( fixX )
GO:0051539 ; 4 iron, 4 sulfur cluster binding ( fixX )
 PID 1786228  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) FIXX_ECOLI ( P31576 ; P75627 )
    -  Protein name Ferredoxin-like protein.  
    -  Synonyms  
    -  Gene name Name=fixX; OrderedLocusNames=b0044, c0054, z0050, ECs0047;  

 Linear View (Whole Mode)
View Location
   35.0  –  60.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fixX (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain B, Formate Dehydrogenase N From E. Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ferredoxin-like protein fixX  
         PSI-BLAST Ferredoxin-like protein
    nr     (database updated : 2007.02.20 )
         BLAST putative ferredoxin [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    COG COG2440C 
    EcoCyc fixX 

MMBR References
J Basic Microbiol. 1995;35(4):217-27.
The fix Escherichia coli region contains four genes related to carnitine metabolism.
Eichler K, Buchet A, Bourgis F, Kleber HP, Mandrand-Berthelot MA. ( 7473063 )
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.

Sequences
Amino acid
FASTA format
0001 MTSPVNVDVK LGVNKFNVDE EHPHIVVKAD ADKQALELLV KACPAGLYKK QDDGSVRFDY AGCLECGTCR 
0071 ILGLGSALEQ WEYPRGTFGV EFRYG

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             GCAGCGCGCC GGAACTGATG CGCAAGAAAA 
-070 TCCTCCGCCA CGGCAAGAAA GTGGGCTTCA TCAATCTAAT CAAGGATGGC ATGAAAGGAG TGACCGTTTT 
0001 atgacttctc ccgtcaatgt ggacgtcaaa ctgggcgtca ataaattcaa tgtcgatgaa gagcatccgc 
0071 acattgttgt gaaggccgat gctgataaac aggcgctgga gctgctggtg aaagcgtgcc ccgcaggtct 
0141 gtacaagaag caggatgacg gcagtgtgcg cttcgattac gccggatgtc tggagtgcgg cacctgtcgc 
0211 attctggggc tggggtcggc gctggaacag tgggaatacc cgcgcggcac ctttggtgtg gagttccgtt 
0281 acggctgaTG TTGGTTTGAT ACGTAACGCC GCACTGACTC TCATTGCAAA AAACAGGAAT AACCATGCAA 
0351 CCGTCCAGAA ACTTTGACGA TCTCAAATTC TCCTCTAT