|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
OCR16,17-3 (BK2-17 / AK1-17)
(D)
,
OCR17
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
hflK
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
hflK
Search strains by all related name:
hflK b4174 ECK4170 hflA hslY JW4132
|
General information (Go to Linear View: )
|
|
Gene Name
|
hflK
|
|
Alternative name
|
b4174,ECK4170,hflA,hslY,JW4132
|
|
Location, Length
|
4,400,061 - 4,401,320
(
+
)
;
94.84
min
;
1260
(bp) ,
419
(aa)
|
|
Product
|
modulator for HflB protease specific for phage lambda cII repressor
|
|
Operon Name
|
yjeFE-amiB-mutL-miaA-hfq-hflXKC
|
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Note
|
protease specific for phage lambda cII repressor
|
|
Function
|
enzyme; Degradation of proteins, peptides, glyco
|
|
Gene Ontology
|
GO:0005515
;
protein binding ( hflK )
GO:0016020
;
membrane ( hflK )
GO:0016021
;
integral to membrane ( hflK )
|
|
PID
|
1790616
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
HFLK_ECOLI
(
P25662
)
|
|
- Protein name
|
HflK protein.
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|
- Synonyms
|
|
|
- Gene name
|
Name=hflK; Synonyms=hflA; OrderedLocusNames=b4174, z5781, ECs5150;
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
hflK
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Protein hflK
|
|
PSI-BLAST
|
Keratin type II cuticular Hb4
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
protease specific for phage lambda cII repressor [Escherichia coli O157:H7 EDL933]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
|
|
MMBR References
|
J Bacteriol. 1987;169(9):4076-85.
Identification of polypeptides encoded by an Escherichia coli locus (hflA) that governs the lysis-lysogeny decision of bacteriophage lambda.
Banuett F, Herskowitz I.
(
3040675
)
|
J Bacteriol. 1973;115(1):299-306.
Genetic and biochemical investigation of the Escherichia coli mutant hfl-1 which is lysogenized at high frequency by bacteriophage lambda.
Belfort M, Wulff DL.
(
4352176
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MAWNQPGNNG QDRDPWGSSK PGGNSEGNGN KGGRDQGPPD LDDIFRKLSK KLGGLGGGKG TGSGGGSSSQ
0071 GPRPQLGGRV VTIAAAAIVI IWAASGFYTI KEAERGVVTR FGKFSHLVEP GLNWKPTFID EVKPVNVEAV
0141 RELAASGVML TSDENVVRVE MNVQYRVTNP EKYLYSVTSP DDSLRQATDS ALRGVIGKYT MDRILTEGRT
0211 VIRSDTQREL EETIRPYDMG ITLLDVNFQA ARPPEEVKAA FDDAIAAREN EQQYIREAEA YTNEVQPRAN
0281 GQAQRILEEA RAYKAQTILE AQGEVARFAK LLPEYKAAPE ITRERLYIET MEKVLGNTRK VLVNDKGGNL
0351 MVLPLDQMLK GGNAPAAKSD NGASNLLRLP PASSSTTSGA SNTSSTSQGD IMDQRRANAQ RNDYQRQGE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GATTACCTGA TCTAACGGCG TAGCGTCTGA
-070 AGCGTGGAGT CATATCCTCT GGCGTCGAAA GACAACAGGG ATCACCGCAT AACAAATATG GAGCACAAAC
0001 atggcgtgga atcagcccgg taataacgga caagaccgcg acccgtgggg aagcagcaaa cctggcggca
0071 actctgaggg aaatggaaac aaaggcggtc gcgatcaagg gccacctgat ttagatgata tcttccgcaa
0141 actgagcaaa aagctcggtg gtctgggcgg cggtaaaggc accggatctg gcggtggcag ttcatcgcaa
0211 ggcccgcgcc cgcagcttgg cggtcgtgtc gttaccatcg cagcggcagc gattgtcatt atctgggcgg
0281 ccagtggttt ctataccatt aaagaagccg aacgcggcgt ggtaacacgc tttggtaaat tcagccatct
0351 ggttgagccg ggtctgaact ggaaaccgac gtttatcgac gaagtcaaac cggtgaacgt ggaagccgtg
0421 cgtgaactgg ccgcttctgg tgtgatgctg acgtcggacg agaacgtagt gcgcgttgag atgaacgtgc
0491 agtaccgcgt caccaatccg gaaaaatatc tgtatagcgt gaccagcccg gatgacagcc tgcgtcaggc
0561 taccgacagc gccctgcgtg gagttatcgg taaatacacc atggaccgca ttctgacgga aggtcgtacc
0631 gtgattcgta gcgatactca gcgcgaactg gaagagacga ttcgtccgta tgacatgggt atcacgctgc
0701 tggacgtcaa cttccaggct gctcgtccgc cggaagaagt aaaagcggcg tttgacgatg cgattgccgc
0771 gcgtgaaaac gaacagcaat acattcgtga agcagaagcg tataccaacg aagttcagcc gcgtgcgaac
0841 ggtcaggcgc aacgtatcct cgaagaggcg cgtgcgtaca aggcccagac catcctggaa gctcagggtg
0911 aagtggcgcg ctttgctaaa cttctgccgg aatataaagc cgcgccggaa attactcgcg agcgtctgta
0981 tatcgagacg atggaaaaag tgttgggtaa cacccgcaaa gtgctggtta acgataaagg tggcaacctg
1051 atggttctgc cgttagacca gatgctgaaa ggtggtaacg cccctgcggc gaagagcgat aacggtgcca
1121 gcaatctgct gcgtctgccg ccagcctctt cctccacaac cagtggagca agcaacacgt cgtccaccag
1191 tcagggcgat attatggacc aacgccgcgc caacgcgcag cgtaacgact accagcgtca gggggaataa
1261 CGATGCGTAA GTCAGTTATC GCGATTATCA TCATCGTGCT GGTAGTGCTT TACATGTCTG TCTTTGTCGT
1331 CAAAGAAGGT GAGCGCGGTA TTACGCTGCG
|
