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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
|
OCR03
(D)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
hemX
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Related strains
|
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Strains Search
|
Search strains by gene name:
hemX
Search strains by all related name:
hemX b3803 ECK3797 JW3775
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General information (Go to Linear View: )
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Gene Name
|
hemX
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Alternative name
|
b3803,ECK3797,JW3775
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Location, Length
|
3,985,908 - 3,987,089
(
-
)
;
85.91
min
;
1182
(bp) ,
393
(aa)
|
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Product
|
putative uroporphyrinogen III methyltransferase
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Operon Name
|
hemCDXY
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Note
|
uroporphyrinogen III methylase
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Function
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enzyme; Biosynthesis of cofactors, carriers: Heme, porphyrin
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Gene Ontology
|
GO:0004851
;
uroporphyrin-III C-methyltransferase activity ( hemX )
GO:0005515
;
protein binding ( hemX )
GO:0005886
;
plasma membrane ( hemX )
GO:0006779
;
porphyrin biosynthetic process ( hemX )
GO:0008168
;
methyltransferase activity ( hemX )
GO:0016020
;
membrane ( hemX )
GO:0016021
;
integral to membrane ( hemX )
GO:0016740
;
transferase activity ( hemX )
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PID
|
1790235
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EC number
(KEGG Pathway)
|
2.1.1.107
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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hemX
(
EG10433
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
HEMX_ECOLI
(
P09127
)
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- Protein name
|
Putative uroporphyrin-III C-methyltransferase
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- Synonyms
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EC 2.1.1.107, Urogen III methylase, ORF X
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- Gene name
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Name=hemX; OrderedLocusNames=b3803;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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hemX
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Putative uroporphyrinogen-III C-methyltransferase
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PSI-BLAST
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Keratin type II cuticular Hb4
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nr
(database updated :
2007.02.20
)
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BLAST
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putative uroporphyrin-III C-methyltransferase [Escherichia coli UTI89]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMIDATION
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MMBR References
|
Nucleic Acids Res. 1988;16(24):11835
Nucleotide sequence of the hemX gene, the third member of the Uro operon of Escherichia coli K12.
Sasarman A, Echelard Y, Letowski J, Tardif D, Drolet M.
(
3062586
)
|
Science. 1992;257(5071):771-8.
Analysis of the Escherichia coli genome: DNA sequence of the region from 84.5 to 86.5 minutes.
Daniels DL, Plunkett G 3rd, Burland VD, Blattner FR.
(
1379743
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTEQEKTSAV VEETREAVDT TSQPVATEKK SKNNTALILS AVAIAIALAA GIGLYGWGKQ QAVNQTATSD
0071 ALANQLTALQ KAQESQKAEL EGIIKQQAAQ LKQANRQQET LAKQLDEVQQ KVATISGSDA KTWLLAQADF
0141 LVKLAGRKLW SDQDVTTAAA LLKSADASLA DMNDPSLITV RRAITDDIAS LSAVSQVDYD GIILKLNQLS
0211 NQVDNLRLAD NDSDGSPMDS DGEELSSSIS EWRINLQKSW QNFMDNFITI RRRDDTAVPL LAPNQDIYLR
0281 ENIRSRLLVA AQAVPRHQEE TYRQALENVS TWVRAYYDTD DATTKAFLDE VDQLSQQNIS MDLPETLQSQ
0351 AMLEKLMQTR VRNLLAQPAA GTTEAKPAPA PQADTPAAAP QGE
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgcccgggaa ctgggctggc aagacattaa
-070 ggtcgccgat aacgctgaca acgatgcgct tttacgggca ttacaataac tctcataaca ggaagccata
0001 atgacggaac aagaaaaaac ctccgccgtg gttgaagaga ccagggaggc cgtggacacc acgtcacaac
0071 ctgtcgcaac agaaaaaaag agtaagaaca ataccgcatt gattctcagc gcggtggcta tcgctattgc
0141 tctggcggcg ggcatcggtt tgtatggctg gggtaaacaa caggccgtca atcagaccgc caccagcgat
0211 gccctggcta accaactgac ggcattgcaa aaagcccagg agagccaaaa agccgagctg gaaggcatta
0281 ttaagcaaca agctgcacaa cttaagcagg cgaatcgtca gcaagaaacg ctggcaaaac agttggatga
0351 agtccaacaa aaggtcgcca ccatttccgg cagcgatgct aaaacctggc tgctggctca ggccgatttt
0421 ctggtgaaac tcgccggacg gaagctgtgg agcgatcagg acgtcacgac cgctgcagcg ttgctgaaaa
0491 gtgcagacgc cagcctggcg gatatgaatg acccgagtct gattaccgtt cgtcgggcaa ttaccgatga
0561 tatcgccagc ctttctgcag tatcgcaggt ggattatgac ggcatcatcc ttaagcttaa tcagctttca
0631 aatcaggtag ataacctgcg tctggccgat aatgacagcg atggttcgcc gatggattca gacggtgaag
0701 agctttccag ttccatcagc gaatggcgta tcaatctgca aaaaagctgg cagaacttta tggacaactt
0771 cattacgatt cgccgtcgtg atgacaccgc cgtaccgctg ttagcgccaa atcaggatat ctatctgcgc
0841 gaaaatattc gctctcgcct gctggtcgca gcacaagctg taccgcgtca ccaggaagag acttatcgcc
0911 aggcgctgga gaacgtctcc acctgggtac gtgcttacta cgatactgat gatgccacca ccaaagcgtt
0981 cctcgacgag gtggaccagt taagccagca aaatatctcg atggatcttc cggaaaccct gcaaagccag
1051 gcgatgctgg aaaaactgat gcagactcgc gtgcgtaacc tgctggcaca accggcagcg gggacaacgg
1121 aagctaaacc tgcacctgca ccgcaagctg atactccggc agccgcgccg caaggagaat aaccatgcta
1191 aaagtgttat tgctctttgt gttgctgatt gcggggatcg tggttggccc gatgattgcc ggccatcagg
1261 gttatgtgct gatccagacc ga
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