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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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DE(nadC-aceF)72
,
DE(aroP-lpd)74
,
OCR31
(D)
,
OCR31-7
(D)
|
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Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
pdhR
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Related strains
|
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Strains Search
|
Search strains by gene name:
pdhR
Search strains by all related name:
pdhR aceC b0113 ECK0112 genA JW0109 yacB
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General information (Go to Linear View: )
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Gene Name
|
pdhR
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Alternative name
|
aceC,b0113,ECK0112,genA,JW0109,yacB
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Location, Length
|
122,092 - 122,856
(
+
)
;
2.63
min
;
765
(bp) ,
254
(aa)
|
|
Product
|
DNA-binding transcriptional dual regulator
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Operon Name
|
pdhR-aceEF-lpd
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Note
|
transcriptional regulator for pyruvate dehydrogenase complex; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006096 - glycolysis; GO_process: GO:0006350 - transcription
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Function
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regulator; Energy metabolism, carbon: Pyruvate dehydrogenase
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Gene Ontology
|
GO:0003677
;
DNA binding ( pdhR )
GO:0003700
;
transcription factor activity ( pdhR )
GO:0005622
;
intracellular ( pdhR )
GO:0006350
;
transcription ( pdhR )
GO:0006355
;
regulation of transcription, DNA-dependent ( pdhR )
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PID
|
1786303
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
PDHR_ECOLI
(
P06957
;
Q53381
)
|
|
- Protein name
|
Pyruvate dehydrogenase complex repressor.
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- Synonyms
|
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- Gene name
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OrderedLocusNames=b0113, c0140, z0123, ECs0117;
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MMBR References
|
FEBS Lett. 1993;336(1):43-7.
A mutation causing constitutive synthesis of the pyruvate dehydrogenase complex in Escherichia coli is located within the pdhR gene.
Haydon DJ, Quail MA, Guest JR.
(
8262214
)
|
Mol Microbiol. 1994;12(1):95-104.
The pdhR-aceEF-lpd operon of Escherichia coli expresses the pyruvate dehydrogenase complex.
Quail MA, Haydon DJ, Guest JR.
(
8057842
)
|
FEMS Microbiol Lett. 1998;159(2):325-9.
Environmental control of pyruvate dehydrogenase complex expression in Escherichia coli.
Cassey B, Guest JR, Attwood MM.
(
9503628
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MAYSKIRQPK LSDVIEQQLE FLILEGTLRP GEKLPPEREL AKQFDVSRPS LREAIQRLEA KGLLLRRQGG
0071 GTFVQSSLWQ SFSDPLVELL SDHPESQYDL LETRHALEGI AAYYAALRST DEDKERIREL HHAIELAQQS
0141 GDLDAESNAV LQYQIAVTEA AHNVVLLHLL RCMEPMLAQN VRQNFELLYS RREMLPLVSS HRTRIFEAIM
0211 AGKPEEAREA SHRHLAFIEE ILLDRSREES RRERSLRRLE QRKN
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Nucleotide
FASTA format
View sequence in neighbor 100bp
|
0001 atggcctaca gcaaaatccg ccaaccaaaa ctctccgatg tgattgagca gcaactggag tttttgatcc
0071 tcgaaggcac tctccgcccg ggcgaaaaac tcccaccgga acgcgaactg gcaaaacagt ttgacgtctc
0141 ccgtccctcc ttgcgtgagg cgattcaacg tctcgaagcg aagggcttgt tgcttcgtcg ccagggtggc
0211 ggcacttttg tccagagcag cctatggcaa agcttcagcg atccgctggt ggagctgctc tccgaccatc
0281 ctgagtcaca gtatgacttg ctcgaaacac gacacgccct ggaaggtatc gccgcttatt acgccgcgct
0351 gcgtagtacc gatgaagaca aggaacgcat ccgtgaactc caccacgcca tagagctggc gcagcagtct
0421 ggcgatctgg acgcggaatc aaacgccgta ctccagtatc agattgccgt caccgaagcg gcccacaatg
0491 tggttctgct tcatctgcta aggtgtatgg agccgatgtt ggcccagaat gtccgccaga acttcgaatt
0561 gctctattcg cgtcgcgaga tgctgccgct ggtgagtagt caccgcaccc gcatatttga agcgattatg
0631 gccggtaagc cggaagaagc gcgcgaagca tcgcatcgcc atctggcctt tatcgaagaa attttgctcg
0701 acagaagtcg tgaagagagc cgccgtgagc gttctctgcg tcgtctggag caacgaaaga attag
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