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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR31
(D)
,
OCR31-2
(D)
,
OCR31-7
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
hofC
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Related strains
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Strains Search
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Search strains by gene name:
hofC
Search strains by all related name:
hofC b0106 ECK0105 f400 hopC JW0102 yacD
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General information (Go to Linear View: )
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Gene Name
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hofC
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Alternative name
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b0106,ECK0105,f400,hopC,JW0102,yacD
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Location, Length
|
114,522 - 115,724
(
-
)
;
2.47
min
;
1203
(bp) ,
400
(aa)
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Product
|
assembly protein in type IV pilin biogenesis, transmembrane protein
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Operon Name
|
ppdD-hofBC
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Note
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putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane
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Function
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putative transport; Not classified
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Gene Ontology
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GO:0005886
;
plasma membrane ( hofC )
GO:0006810
;
transport ( hofC )
GO:0008565
;
protein transporter activity ( hofC )
GO:0009306
;
protein secretion ( hofC )
GO:0015627
;
type II protein secretion system complex ( hofC )
GO:0015628
;
protein secretion by the type II secretion system ( hofC )
GO:0016020
;
membrane ( hofC )
GO:0016021
;
integral to membrane ( hofC )
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PID
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1786295
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show simple
)
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Entry name(Acc.no)
|
HOFC_ECOLI
(
P36646
;
P75648; Q47020; Q47021
)
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- Protein name
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Protein transport protein hofC.
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- Synonyms
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- Gene name
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Name=hofC; Synonyms=hopC; OrderedLocusNames=b0106;
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- Comments
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SUBCELLULAR LOCATION:Integral membrane protein. Inner membrane (Probable).
SIMILARITY:Belongs to the pulF/outF/exeF/xpsF/xcpS family.
CAUTION:Ref.2 and Ref.4 sequences differ in the N- and C-terminal as well as in the central part due to frameshifts.
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Entry name(Acc.no)
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Q8FL54
(
Q8FL54
)
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- Protein name
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Protein transport protein hofC.
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- Synonyms
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- Gene name
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Name=hofC; OrderedLocusNames=c0125;
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- Comments
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SUBCELLULAR LOCATION:Integral membrane protein (By similarity).
SIMILARITY:BELONGS TO THE PULF/OUTF/EXEF/XPSF/XCPS FAMILY.
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Entry name(Acc.no)
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Q8X977
(
Q8X977
)
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- Protein name
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Putative integral membrane protein involved in biogenesis of fimbriae, protein transport, DNA uptake.
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- Synonyms
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- Gene name
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Name=hofC; OrderedLocusNames=z0116;
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- Comments
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SUBCELLULAR LOCATION:Integral membrane protein (By similarity).
SIMILARITY:BELONGS TO THE PULF/OUTF/EXEF/XPSF/XCPS FAMILY.
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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hofC
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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Protein transport protein hofC
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PSI-BLAST
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General secretion pathway protein F
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nr
(database updated :
2007.02.20
)
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BLAST
|
assembly protein in type IV pilin biogenesis, transmembrane protein [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
|
GLYCOSAMINOGLYCAN
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
RGD
LEUCINE_ZIPPER
T2SP_F
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MMBR References
|
Gene. 1994;150(1):9-15.
Escherichia coli contains a set of genes homologous to those involved in protein secretion, DNA uptake and the assembly of type-4 fimbriae in other bacteria.
Whitchurch CB, Mattick JS.
(
7959070
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MASKQLWRWH GITGDGNAQD GMLWAESRTL LLMALQQQMV TPLSLKRIAI NSAQWRGDKS AEVIHQLATL
0071 LKAGLTLSEG LALLAEQHPS KQWQALLQSL AHDLEQGIAF SNALLPWSEV FPPLYQAMIR TGELTGKLDE
0141 CCFELARQQK AQRQLTDKVK SALRYPIIIL AMAIMVVVAM LHFVLPEFAA IYKTFNTPLP ALTQGIMTLA
0211 DFSGEWSWLL VLFGFLLAIA NKLLMRRPTW LIVRQKLLLR IPIMGSLMRG QKLTQIFTIL ALTQSAGITF
0281 LQGVESVRET MRCPYWVQLL TQIQHDISNG QPIWLALKNT GEFSPLCLQL VRTGEASGSL DLMLDNLAHH
0351 HRENTMALAD NLAALLEPAL LIITGGIIGT LVVAMYLPIF HLGDAMSGMG
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgacaggcgg gtatgcgtac gctttttgaa
-070 aacggctgcc tggccgtaga gcaaggctta accacctttg aagagttaat ccgcgtactg gggatgccgc
0001 atggcgagta agcaactctg gcgctggcat ggcataaccg gcgacggcaa tgcgcaagat gggatgctat
0071 gggcagagag ccgtacttta ctgcttatgg cactacagca acagatggtt accccactaa gcctgaagcg
0141 aatcgccatc aattctgcgc agtggcgagg agataaaagc gcggaagtca ttcatcaact ggcgacgcta
0211 ctcaaagcag ggttaacgct ttctgaaggg ctggctctgc tggcggaaca gcatcccagt aagcaatggc
0281 aagcgttgct gcaatcgctg gcgcacgatc tcgaacaggg cattgctttt tccaatgcct tattaccctg
0351 gtcagaggta tttccgccgc tctatcaggc gatgatccgc acgggtgaac tgaccggtaa gctggatgaa
0421 tgctgctttg aactggcgcg tcagcaaaaa gcccagcgtc agttgaccga caaagtgaaa tcagcgttac
0491 gttatcccat catcatttta gcgatggcaa tcatggtggt tgtggcaatg ctgcattttg ttctgccgga
0561 gtttgccgct atctataaga ccttcaacac cccactaccg gcactaacgc aggggatcat gacgctggca
0631 gactttagtg gcgaatggag ctggctgctg gtgttgttcg gctttctgct ggcgatagcc aataagttgc
0701 tgatgcgccg accgacctgg cttatagtgc ggcagaaatt gctgttacgc atcccgatta tgggttcact
0771 gatgcgggga caaaaactca cgcagatctt tacgattctg gcgctgacac aaagtgcagg cattactttt
0841 ttacagggcg tagagagcgt cagagaaaca atgcgctgcc cgtactgggt gcaacttctg acacaaatcc
0911 agcacgatat cagtaacggt caacccatct ggctggcgct aaaaaatacc ggtgagttta gcccgctctg
0981 tttgcaatta gtgagaacag gagaggcatc cggctctctg gatctcatgt tagacaacct cgcccatcat
1051 catcgggaaa acacaatggc gctggcggat aacctcgcag ccttactgga accggcgttg ctgatcataa
1121 cgggaggaat tattggtacg ctggtggtgg caatgtatct gccaattttc catttaggcg atgcgatgag
1191 tgggatggga taacgctggc gtgttgctcc acgccagcgt tgggagatta caggttgttg aagatgcggt
1261 tttcttgttc ctgcacacga ataaacgtgg tgcgcttggt cag
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