MG1655
W3110
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Gene Report : caiB
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCR28 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  caiB
Related strains
     Strains Search Search strains by gene name:  caiB   Search strains by all related name:  caiB b0038 ECK0039 JW0037 yaaN

General information  (Go to Linear View:)
 Gene Name caiB  
 Alternative name b0038,ECK0039,JW0037,yaaN  
 Location, Length 37,898 - 39,115 (  -  ) ;   0.82 min ; 1218 (bp) ,   405 (aa) Go to Linear View
 Product crotonobetainyl CoA:carnitine CoA transferase  
 Operon Name caiTABCDE  
 Note l-carnitine dehydratase; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0042413 - carnitine catabolic process; GO_process: GO:0009310 - amine catabolic process  
 Function enzyme; Central intermediary metabolism: Pool, multipurpose conversions  
 Gene Ontology GO:0003824 ; catalytic activity ( caiB )
GO:0005737 ; cytoplasm ( caiB )
GO:0008152 ; metabolic process ( caiB )
GO:0008410 ; CoA-transferase activity ( caiB )
GO:0016740 ; transferase activity ( caiB )
 PID 1786222  
 EC number
  (KEGG Pathway)   		2.8.3.-  
Verified Protein Starts (data compiled from literature and appropriate citations are available from EcoGene)
     EcoGene caiB ( EG11559 )  
    Number of removed 0 aa cleaved  
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) CAIB_ECOLI ( P31572 )
    -  Protein name Crotonobetainyl-CoA:carnitine CoA-transferase  
    -  Synonyms EC 2.8.3.-  
    -  Gene name Name=caiB; OrderedLocusNames=b0038;  

 Linear View (Whole Mode)
View Location
   37.898  –  62.898 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP caiB (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of Caib Mutant D169a In Complex With Coenzyme A  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Crotonobetainyl-CoA:carnitine CoA-transferase  
         PSI-BLAST Crotonobetainyl-CoA:carnitine CoA-transferase
    nr     (database updated : 2007.02.20 )
         BLAST crotonobetainyl-CoA:carnitineCoA-transferase [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE GLYCOSAMINOGLYCAN    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL     

Other Cross-Reference
    COG COG1804C 
    EcoCyc caiB 

MMBR References
J Bacteriol. 1994;176:2970-2975
Cloning, nucleotide sequence, and expression of the Escherichia coli gene encoding carnitine dehydratase.
Eichler, K., W.-H. Schunck, H.-P. Kleber, and M. A. Mandrand-Berthelot.
J Bacteriol. 1998;180:2599-2608
Regulation of the carnitine pathway in Escherichia coli: investigation of the cai-fix divergent promoter region.
Buchet, A., K. Eichler, and M. A. Mandrand-Berthelot.

Sequences
Amino acid
FASTA format 
0001 MDHLPMPKFG PLAGLRVVFS GIEIAGPFAG QMFAEWGAEV IWIENVAWAD TIRVQPNYPQ LSRRNLHALS 
0071 LNIFKDEGRE AFLKLMETTD IFIEASKGPA FARRGITDEV LWQHNPKLVI AHLSGFGQYG TEEYTNLPAY 
0141 NTIAQAFSGY LIQNGDVDQP MPAFPYTADY FSGLTATTAA LAALHKVRET GKGESIDIAM YEVMLRMGQY 
0211 FMMDYFNGGE MCPRMSKGKD PYYAGCGLYK CADGYIVMEL VGITQIEECF KDIGLAHLLG TPEIPEGTQL 
0281 IHRIECPYGP LVEEKLDAWL ATHTIAEVKE RFAELNIACA KVLTVPELES NPQYVARESI TQWQTMDGRT 
0351 CKGPNIMPKF KNNPGQIWRG MPSHGMDTAA ILKNIGYSEN DIQELVSKGL AKVED
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             tgcgtcttat caggcctacg ggagcacgaa 
-070 tgtaggccgg ataaagcgtt tacgccgcat ccggcagtca tgcgctacat aaatttttca ggagcaaata 
0001 atggatcatc tacccatgcc gaaattcggg ccgttggccg gattgcgcgt tgtcttctcc ggtatcgaaa 
0071 tcgccggacc gtttgccggg caaatgttcg cagaatgggg cgcggaagtt atctggatcg agaacgtcgc 
0141 ctgggccgac accattcgcg ttcaaccgaa ctacccgcaa ctctcccgcc gcaatttgca cgcgctgtcg 
0211 ttaaatattt tcaaagatga aggccgcgaa gcgtttctga aattaatgga aaccaccgat atcttcatcg 
0281 aagccagtaa aggtccggcc tttgcccgtc gtggcattac cgatgaagta ctgtggcagc acaacccgaa 
0351 actggttatc gctcacctgt ccggttttgg tcagtacggc accgaggagt acaccaatct tccggcctat 
0421 aacactatcg cccaggcctt tagtggttac ctgattcaga acggtgatgt tgaccagcca atgcctgcct 
0491 tcccgtatac cgccgattac ttttctggcc tgaccgccac cacggcggcg ctggcagcac tgcataaagt 
0561 gcgtgaaacc ggtaaaggcg aaagtatcga catcgccatg tatgaagtga tgctgcgtat gggccagtac 
0631 ttcatgatgg attacttcaa cggcggcgaa atgtgcccgc gcatgagcaa aggtaaagat ccctactacg 
0701 ccggttgcgg tctgtataaa tgtgccgacg gctacatcgt gatggaactg gtgggcatta cccaaattga 
0771 agagtgcttt aaagatattg gcctcgcaca tctgcttggc acgccagaaa tcccggaagg cactcagctt 
0841 atccaccgta tcgaatgccc ttacggccca ctggttgaag agaaactcga tgcctggctg gcgacacata 
0911 ccatcgcgga agtaaaagaa cgctttgctg aactgaatat cgcctgcgcc aaagtgctga ccgtaccgga 
0981 actggaaagc aatccacagt atgtggctcg cgaatcaatc actcagtggc aaacgatgga tggtcgcacc 
1051 tgcaaagggc cgaacatcat gccgaaattc aaaaataacc ccggacaaat ctggcgcgga atgccctcac 
1121 atggcatgga cacggctgcc attttgaaaa atatcggcta cagcgaaaac gacattcagg agttggtcag 
1191 caaaggtctg gccaaagttg aggactaaac gcgtggcgtc agtcggcttg cctgactagc gcccgcccaa 
1261 taacaaacga acaaaaatgg atagaggtgc aatggatatc attggcggac aacatcta