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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Deletion
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OCR31
(D)
,
OCR31-2
(D)
,
OCR31-7
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
nadC
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Related strains
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Strains Search
|
Search strains by gene name:
nadC
Search strains by all related name:
nadC b0109 ECK0108 JW0105
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General information (Go to Linear View: )
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Gene Name
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nadC
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Alternative name
|
b0109,ECK0108,JW0105
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Location, Length
|
117,752 - 118,645
(
-
)
;
2.54
min
;
894
(bp) ,
297
(aa)
|
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Product
|
quinolinate phosphoribosyltransferase
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Operon Name
|
nadC
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Note
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GO_process: GO:0009435 - NAD biosynthetic process
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Function
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enzyme; Biosynthesis of cofactors, carriers: Pyridine nucleotide
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Gene Ontology
|
GO:0003824
;
catalytic activity ( nadC )
GO:0004514
;
nicotinate-nucleotide diphosphorylase (carboxylating) activity ( nadC )
GO:0005515
;
protein binding ( nadC )
GO:0008152
;
metabolic process ( nadC )
GO:0009435
;
NAD biosynthetic process ( nadC )
GO:0016740
;
transferase activity ( nadC )
GO:0016757
;
transferase activity, transferring glycosyl groups ( nadC )
GO:0019363
;
pyridine nucleotide biosynthetic process ( nadC )
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PID
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1786299
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EC number
(KEGG Pathway)
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2.4.2.19
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
NADC_ECOLI
(
P30011
)
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- Protein name
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Nicotinate-nucleotide pyrophosphorylase [carboxylating]
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- Synonyms
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EC 2.4.2.19, Quinolinate phosphoribosyltransferase [decarboxylating], QAPRTase
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- Gene name
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Name=nadC; OrderedLocusNames=b0109;
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MMBR References
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J Gen Microbiol. 1980;121(2):277-92.
Molecular cloning of the pyruvate dehydrogenase complex genes of Escherichia coli.
Guest JR, Stephens PE.
(
6455499
)
|
J Gen Microbiol. 1983;129(3):671-80.
Hybrid plasmids containing the pyruvate dehydrogenase complex genes and gene-DNA relationships in the 2 to 3 minute region of the Escherichia coli chromosome.
Guest JR, Roberts RE, Stephens PE.
(
6308128
)
|
J Gen Microbiol. 1981;127:65-79.
Organization and expression of the pyruvate dehydrogenase complex genes of Escherichia coli K12.
Guest, J. R., S. T. Cole, and K. Jeyaseelan.
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J Gen Microbiol. 1977;99(2):263-76.
Biochemical genetics of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: isolation and biochemical properties of deletion mutants.
Langley D, Guest JR.
(
327021
)
|
J Gen Microbiol. 1978;106(1):103-17.
Biochemical genetics of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: genetic characterization and regulatory properties of deletion mutants.
Langley D, Guest JR.
(
349114
)
|
J Bacteriol. 1988;170(1):463-7.
Genetic and molecular characterization of the guaC-nadC-aroP region of Escherichia coli K-12.
Roberts RE, Lienhard CI, Gaines CG, Smith JM, Guest JR.
(
3275629
)
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| Sequences |
Amino acid
FASTA format
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0001 MPPRRYNPDT RRDELLERIN LDIPGAVAQA LREDLGGTVD ANNDITAKLL PENSRSHATV ITRENGVFCG
0071 KRWVEEVFIQ LAGDDVTIIW HVDDGDVINA NQSLFELEGP SRVLLTGERT ALNFVQTLSG VASKVRHYVE
0141 LLEGTNTQLL DTRKTLPGLR SALKYAVLCG GGANHRLGLS DAFLIKENHI IASGSVRQAV EKASWLHPDA
0211 PVEVEVENLE ELDEALKAGA DIIMLDNFET EQMREAVKRT NGKALLEVSG NVTDKTLREF AETGVDFISV
0281 GALTKHVQAL DLSMRFR
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gttctaacaa catgcaggat ctccttatat
-070 gtggtgctaa tacccggttc agagtagcat gtttctacct tatgattcgt tagctatctg gagttttaac
0001 atgccgcctc gccgctataa ccctgacacc cgacgtgacg agctgctgga acgcattaat ctcgatatcc
0071 ccggcgcggt ggcccaggcg ctgcgggaag atttaggcgg aacagtcgat gccaacaatg atattacggc
0141 aaaactttta ccggaaaatt ctcgctctca tgccacggtg atcacccgcg agaatggcgt cttttgcggc
0211 aaacgctggg ttgaagaggt gtttattcaa ctggcaggcg acgatgtcac cataatctgg catgtggatg
0281 acggcgatgt catcaatgcc aatcaatcct tgttcgaact tgaaggccca tcccgcgtgc tgttaacggg
0351 cgaacgcact gcgcttaatt ttgtgcaaac cctttcagga gttgccagta aggtacgcca ctatgtcgaa
0421 ttgctggaag gcaccaacac gcagttgttg gatacgcgca aaaccttacc cggcctgcgt tcagctctga
0491 aatacgcggt actttgcggc ggcggagcga atcaccgtct ggggctttct gatgccttcc tgatcaaaga
0561 aaaccatatt attgcctccg gctcagtgcg ccaggcggtc gaaaaagcgt cctggctgca cccggatgcg
0631 ccagtagaag tcgaagtaga gaatctggaa gaacttgatg aagccctgaa agcaggagcc gatatcatca
0701 tgctggataa cttcgaaaca gaacagatgc gcgaagccgt caaacgcacc aacggcaagg cgctactgga
0771 agtgtctggc aacgtcactg acaaaacact gcgtgaattt gccgaaacgg gcgtggactt tatctccgtc
0841 ggtgcgctaa ctaaacacgt acaagcactc gacctttcaa tgcgttttcg ctaatagttg acagatttat
0911 ccgctccatc gcgggcggat aatctcccct tccccaactt tcttcgtaac gcctcgcaaa tttcttgtct
0981 ttcgctgcaa cgaa
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