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RRC ID 65236
著者 Shin MG, Lee JW, Han JS, Lee B, Jeong JH, Park SH, Kim JH, Jang S, Park M, Kim SY, Kim S, Yang YR, Kim JY, Hoe KL, Park C, Lee KP, Kwon KS, Kwon ES.
タイトル Bacteria-derived metabolite, methylglyoxal, modulates the longevity of C. elegans through TORC2/SGK-1/DAF-16 signaling.
ジャーナル Proc Natl Acad Sci U S A
巻・号 117(29)
ページ 17142-17150
公開日 2020-7-21
DOI 10.1073/pnas.1915719117
PII 1915719117
PMID 32636256
PMC PMC7382248
MeSH Animals Caenorhabditis elegans* / drug effects Caenorhabditis elegans* / metabolism Caenorhabditis elegans* / microbiology Caenorhabditis elegans Proteins / metabolism* Escherichia coli / metabolism Forkhead Transcription Factors / metabolism* Gastrointestinal Microbiome / physiology Longevity / drug effects* Mechanistic Target of Rapamycin Complex 2 / metabolism Models, Biological Protein Serine-Threonine Kinases / metabolism* Pyruvaldehyde* / metabolism Pyruvaldehyde* / pharmacology Signal Transduction / drug effects Transcriptome / genetics
リソース情報
線虫 tm1108