| RRC ID |
64694
|
| 著者 |
Yassumoto TI, Nakatsukasa M, Nagano AJ, Yasugi M, Yoshimura T, Shinomiya A.
|
| タイトル |
Genetic analysis of body weight in wild populations of medaka fish from different latitudes.
|
| ジャーナル |
PLOS ONE
|
| Abstract |
The genetic bases of growth and body weight are of economic and scientific interest, and teleost fish models have proven useful in such investigations. The Oryzias latipes species complex (medaka) is an abundant freshwater fish in Japan and suitable for genetic studies. We compared two wild medaka stocks originating from different latitudes. The Maizuru population from higher latitudes weighed more than the Ginoza population. We investigated the genetic basis of body weight, using quantitative trait locus (QTL) analysis of the F2 offspring of these populations. We detected one statistically significant QTL for body weight on medaka chromosome 4 and identified 12 candidate genes that might be associated with body weight or growth. Nine of these 12 genes had at least one single nucleotide polymorphism that caused amino acid substitutions in protein-coding regions, and we estimated the effects of these substitutions. The present findings might contribute to the marker-assisted selection of economically important aquaculture species.
|
| 巻・号 |
15(6)
|
| ページ |
e0234803
|
| 公開日 |
2020-1-1
|
| DOI |
10.1371/journal.pone.0234803
|
| PII |
PONE-D-20-01808
|
| PMID |
32544202
|
| IF |
2.74
|
| リソース情報 |
| メダカ |
Maizuru (WS215)
Ginoza (WS255) |
