論文 - 詳細
RRC ID | 3575 |
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著者 | Gorjánácz M, Jaedicke A, Mattaj IW. |
タイトル | What can Caenorhabditis elegans tell us about the nuclear envelope? |
ジャーナル | FEBS Lett |
Abstract |
The nuclear envelope (NE) of the eukaryotic cell provides an essential barrier that separates the nuclear compartment from the cytoplasm. In addition, the NE is involved in essential functions such as nuclear stability, regulation of gene expression, centrosome separation and nuclear migration and positioning. In metazoa the NE breaks down and re-assembles around the segregated chromatids during each cell division. In this review we discuss the molecular constituents of the Caenorhabditis elegans NE and describe their role in post-mitotic NE re-formation, as well as the usefulness of C. elegans as an in vivo system for analyzing NE dynamics. |
巻・号 | 581(15) |
ページ | 2794-801 |
公開日 | 2007-6-19 |
DOI | 10.1016/j.febslet.2007.03.052 |
PII | S0014-5793(07)00325-0 |
PMID | 17418822 |
MeSH | Animals Animals, Genetically Modified Caenorhabditis elegans / embryology Caenorhabditis elegans / genetics Caenorhabditis elegans / metabolism* Caenorhabditis elegans / ultrastructure* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism Microscopy, Electron, Transmission Mitosis Models, Biological Nuclear Envelope / metabolism* Nuclear Envelope / ultrastructure* Nuclear Pore / metabolism Nuclear Pore / ultrastructure Nuclear Proteins / genetics Nuclear Proteins / metabolism RNA Interference |
IF | 3.057 |
引用数 | 23 |
WOS 分野 | BIOCHEMISTRY & MOLECULAR BIOLOGY BIOPHYSICS CELL BIOLOGY |
リソース情報 | |
線虫 | tm1845 |