RRC ID 3575
著者 Gorjánácz M, Jaedicke A, Mattaj IW.
タイトル What can Caenorhabditis elegans tell us about the nuclear envelope?
ジャーナル FEBS Lett
Abstract The nuclear envelope (NE) of the eukaryotic cell provides an essential barrier that separates the nuclear compartment from the cytoplasm. In addition, the NE is involved in essential functions such as nuclear stability, regulation of gene expression, centrosome separation and nuclear migration and positioning. In metazoa the NE breaks down and re-assembles around the segregated chromatids during each cell division. In this review we discuss the molecular constituents of the Caenorhabditis elegans NE and describe their role in post-mitotic NE re-formation, as well as the usefulness of C. elegans as an in vivo system for analyzing NE dynamics.
巻・号 581(15)
ページ 2794-801
公開日 2007-6-19
DOI 10.1016/j.febslet.2007.03.052
PII S0014-5793(07)00325-0
PMID 17418822
MeSH Animals Animals, Genetically Modified Caenorhabditis elegans / embryology Caenorhabditis elegans / genetics Caenorhabditis elegans / metabolism* Caenorhabditis elegans / ultrastructure* Caenorhabditis elegans Proteins / genetics Caenorhabditis elegans Proteins / metabolism Microscopy, Electron, Transmission Mitosis Models, Biological Nuclear Envelope / metabolism* Nuclear Envelope / ultrastructure* Nuclear Pore / metabolism Nuclear Pore / ultrastructure Nuclear Proteins / genetics Nuclear Proteins / metabolism RNA Interference
IF 3.057
引用数 23
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY BIOPHYSICS CELL BIOLOGY
リソース情報
線虫 tm1845