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| 文献 | ||
|---|---|---|
| 著者 | Chen X., Liu X., Zhao Y., Zhou D.X. | |
| タイトル | Histone H3K4me3 and H3K27me3 regulatory genes control stable transmission of an epimutation in rice. | |
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Abstract: DNA methylation loss can produce inheritable active epialleles in plants. The mechanism involved in the stable transmission of hypomethylated epimuations is presently not clear. Here we show that maintenance of a stably hypomethylated active epiallele in rice required a CHD3 protein (CHR729) and that over-expression of an H3K4me3 demethylase (JMJ703) or H3K27me3 methyltransferase (SDG711) could stably resilence the epiallele. CHR729 and JMJ703 have antagonistic function in H3K4me3 in maintaining the active state of the epiallele, whereas SDG711-mediated H3K27me3 was sufficient to stably repress the locus. The data suggest that H3K4me3 and H3K27me3 controlled by these chromatin regulators may be involved in stable transmission/resetting of epigenetic variation in rice. |
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| 掲載誌 | Sci Rep | |
| Country | China | |
| 刊数 | 5 | |
| ページ | 13251 | |
| 発刊年 | 2015 | |
| PubMed ID | 26285801 | |
| PubMed Central ID | 4541256 | |
| DOI | 10.1038/srep13251 | |
| URL | - | |
| 関連情報 | ||
| 遺伝子 | CLF RFS _ | |
| INSD | - | |
| 系統 |
野生イネ コアコレクション |
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| 突然変異系統(遺伝研 Collection) | - | |
| 種子不稔系統 | - | |
| 致死変異体系統 | - | |
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組織別発生段階 - 突然変異系統(遺伝子) |
- | |
| 栽培イネ品種(遺伝研 Collection) | - | |
| 組織別発生段階 | - | |
