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Tg(insulin:EGFP-NTR)
| Strain information | |
|---|---|
| Strain ID | TG1679 |
| Strain Name | Tg(insulin:EGFP-NTR) |
| Strain Type | Transgenics |
| Characteristics | Langerhans island (b cells) of the pancreas express EGFP. Also, these cells are able to be ablated by NTR (metronidazole) treatment. |
Journal
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| Special affairs [Address] |
■ The RECIPIENT shall refer the following publication in any PUBLICATIONS. (Name of the Publication:Ohtsuka T, Takeda H. Targeted ablation of pancreatic b cells in medaka. Zoological Science, 34(3), 179-184 (2015).) |
| Category | Transgenic strains |
| Organization | National Institute for Basic Biology |
| Frozen sperm in NIBB | ○ |
| Deposited by | University of Tokyo |
| Order |
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| Image |
Construct for insulin-NTR Tg.jpg 3 kB promoter region upstream of the medaka insulin gene fused with EGFP and NTR |
| Image |
TG1679.jpg GFP expression in the Tg (ins-EGFP-NTR) Lateral view of a dissected pancreas of the Tg (ins-EGFP-NTR) adult fish. GFP is expressed both in the primary islet (Pi) and secondary islets (arrows). Anterior to the left. Scale bar, 200 µm. |
