|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Gene. 1993;126(1):115-7.
Deletion mutations in the speED operon: spermidine is not essential for the growth of Escherichia coli.
Xie QW, Tabor CW, Tabor H.
(
8472951
)
|
|
|
Deletion
|
OCR32
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
speD
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
speD
Search strains by all related name:
speD b0120 ECK0119 JW0116
|
General information (Go to Linear View: )
|
|
Gene Name
|
speD
|
|
Alternative name
|
b0120,ECK0119,JW0116
|
|
Location, Length
|
134,788 - 135,582
(
-
)
;
2.91
min
;
795
(bp) ,
264
(aa)
|
|
Product
|
S-adenosylmethionine decarboxylase
|
|
Operon Name
|
yacC-speED
|
|
Note
|
GO_process: GO:0006596 - polyamine biosynthetic process
|
|
Function
|
enzyme; Central intermediary metabolism: Polyamine biosynthesis
|
|
Gene Ontology
|
GO:0000287
;
magnesium ion binding ( speD )
GO:0004014
;
adenosylmethionine decarboxylase activity ( speD )
GO:0008295
;
spermidine biosynthetic process ( speD )
GO:0016829
;
lyase activity ( speD )
GO:0016831
;
carboxy-lyase activity ( speD )
|
|
PID
|
1786311
|
EC number
(KEGG Pathway)
|
4.1.1.50
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
speD
(
EG10962
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
SPED_ECOLI
(
P09159
)
|
|
- Protein name
|
S-adenosylmethionine decarboxylase proenzyme
|
|
- Synonyms
|
EC 4.1.1.50, AdoMetDC, SamDC
|
|
- Gene name
|
Name=speD; OrderedLocusNames=b0120, z0130, ECs0124, SF0117, S0119;
|
|
MMBR References
|
J Biol Chem. 1987;262:16037-16040
The speEspeD operon of Escherichia coli. Formation and processing of a proenzyme form of S adenosylmethionine decarboxylase.
Tabor, C. W., and H. Tabor.
|
Proc Natl Acad Sci U S A. 1986;83:6040-6044
Spermidine synthase of Escherichia coli: localization of the speE gene.
Tabor, C. W., H. Tabor, and Q.-W. Xie.
|
| Sequences |
Amino acid
FASTA format
|
0001 MKKLKLHGFN NLTKSLSFCI YDICYAKTAE ERDGYIAYID ELYNANRLTE ILSETCSIIG ANILNIARQD
0071 YEPQGASVTI LVSEEPVDPK LIDKTEHPGP LPETVVAHLD KSHICVHTYP ESHPEGGLCT FRADIEVSTC
0141 GVISPLKALN YLIHQLESDI VTIDYRVRGF TRDINGMKHF IDHEINSIQN FMSDDMKALY DMVDVNVYQE
0211 NIFHTKMLLK EFDLKHYMFH TKPEDLTDSE RQEITAALWK EMREIYYGRN MPAV
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ccgttattac aatccggcaa tccatacggc
-070 agcttttgcc ttacctcagt atctgcaaga cgcactggct tcacagccgt cctaaggaga agataagaaa
0001 ttgaaaaaac tgaaactgca tggctttaat aatctgacca aaagtctgag tttttgtatt tacgatatct
0071 gctacgccaa aactgccgaa gagcgcgacg gttatattgc ttatatcgat gaactctata atgccaaccg
0141 tctgaccgaa atcctgtcag aaacctgttc cattatcggg gctaatattc ttaacatcgc ccgccaggat
0211 tacgaaccac agggtgccag cgtcactatt ctggtgagtg aagaaccggt tgacccgaaa ctcatcgaca
0281 aaacagaaca ccccggccca ctgccagaaa cggtcgttgc ccatcttgat aaaagtcata tttgcgtaca
0351 tacctacccg gaaagtcatc ctgaaggcgg tttatgtacc ttccgcgccg atattgaagt ctctacctgc
0421 ggcgtgattt ctccgctgaa ggcgctgaat tacctgatcc accagcttga gtccgatatc gtaaccattg
0491 attatcgcgt gcgcggtttt acccgcgaca ttaacggtat gaagcacttt atcgaccatg agattaattc
0561 gattcagaac tttatgtctg acgatatgaa ggcgctgtat gacatggtgg atgtgaacgt ctatcaggaa
0631 aatatcttcc ataccaagat gttgcttaaa gagttcgacc ttaagcacta catgttccac accaaaccgg
0701 aagacttaac cgacagcgag cgccaggaaa ttaccgctgc gctgtggaaa gaaatgcgcg agatttatta
0771 cgggcgcaat atgccagctg tttaacggct ctggcggagc tcccaggctc cgccagattt atttacttct
0841 gctgcacgaa attgcggtaa gccgccacga cctgcagaaa atcctcaacg ccgca
|
