PEC Original Annotations
|
Essentiality
|
Class
|
essential
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
Deletion
|
OCR39
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
ribD
|
Related strains
|
Strains Search
|
Search strains by gene name:
ribD
Search strains by all related name:
ribD b0414 ECK0408 JW0404 ribG ybaE
|
General information (Go to Linear View:)
|
Gene Name
|
ribD
|
Alternative name
|
b0414,ECK0408,JW0404,ribG,ybaE
|
Location, Length
|
432,679 - 433,782
(
+
)
;
9.33
min
;
1104
(bp) ,
367
(aa)
|
Product
|
fused diaminohydroxyphosphoribosylaminopyrimidine deaminase and 5-amino-6-(5-phosphoribosylamino) uracil reductase
|
Operon Name
|
nrdR-ribDE-nusB-thiL-pgpA
|
Note
|
|
Function
|
enzyme; Biosynthesis of cofactors, carriers: Riboflavin
|
Gene Ontology
|
GO:0003824
;
catalytic activity ( ribD )
GO:0005215
;
transporter activity ( ybaE )
GO:0006810
;
transport ( ybaE )
GO:0008270
;
zinc ion binding ( ribD )
GO:0008703
;
5-amino-6-(5-phosphoribosylamino)uracil reductase activity ( ribD )
GO:0008835
;
diaminohydroxyphosphoribosylaminopyrimidine deaminase activity ( ribD )
GO:0009231
;
riboflavin biosynthetic process ( ribD )
GO:0016491
;
oxidoreductase activity ( ribD )
GO:0016787
;
hydrolase activity ( ribD )
GO:0046872
;
metal ion binding ( ribD )
GO:0050661
;
NADP binding ( ribD )
|
PID
|
1786616
|
EC number
(KEGG Pathway)
|
1.1.1.193
3.5.4.26
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
RIBD_ECOLI
(
P25539
)
|
- Protein name
|
Riboflavin biosynthesis protein ribD
|
- Synonyms
|
|
- Gene name
|
Name=ribD; Synonyms=ribG; OrderedLocusNames=b0414;
|
MMBR References
|
J Bacteriol. 1997;179:2022-2028
Biosynthesis of riboflavin: characterization of the bifunctional deaminase-reductase of Escherichia coli and Bacillus subtilis.
Richter, G., M. Fischer, C. Krieger, S. Eberhardt, H. Luttgen, I. Gerstenschlager, and A. Bacher.
|
Mol Gen Genet. 1992;234(3):429-32.
Insertional disruption of the nusB (ssyB) gene leads to cold-sensitive growth of Escherichia coli and suppression of the secY24 mutation.
Taura T, Ueguchi C, Shiba K, Ito K.
(
1406588
)
|
Sequences |
Amino acid
FASTA format
|
0001 MQDEYYMARA LKLAQRGRFT THPNPNVGCV IVKDGEIVGE GYHQRAGEPH AEVHALRMAG EKAKGATAYV
0071 TLEPCSHHGR TPPCCDALIA AGVARVVASM QDPNPQVAGR GLYRLQQAGI DVSHGLMMSE AEQLNKGFLK
0141 RMRTGFPYIQ LKLGASLDGR TAMASGESQW ITSPQARRDV QLLRAQSHAI LTSSATVLAD DPALTVRWSE
0211 LDEQTQALYP QQNLRQPIRI VIDSQNRVTP VHRIVQQPGE TWFARTQEDS REWPETVRTL LIPEHKGHLD
0281 LVVLMMQLGK QQINSIWVEA GPTLAGALLQ AGLVDELIVY IAPKLLGSDA RGLCTLPGLE KLADAPQFKF
0351 KEIRHVGPDV CLHLVGA
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GCTCGATAAA GTCGCCTATA TCCGTTTTGC
-070 CTCTGTCTAC CGCAGTTTCG AAGATATCAA AGAATTTGGC GAAGAGATCG CGCGCCTGGA GGACTAAGCC
0001 gtgcaggacg agtattacat ggcgcgggcg ctaaagctgg cgcaacgagg acgttttacc acgcatccca
0071 acccgaatgt cgggtgcgtc attgtcaaag atggcgaaat tgtcggtgaa ggttaccacc aacgtgcggg
0141 tgaaccacat gccgaagtac acgcgttgcg tatggcgggt gaaaaagcca aaggtgcgac cgcctatgtc
0211 acactcgaac cctgtagcca tcatggtcgt acgccaccgt gctgtgacgc actcatcgcc gctggcgtag
0281 cgcgcgtggt tgcctcgatg caagatccta acccgcaggt cgctgggcgt ggactttacc gtctgcaaca
0351 ggctggcatt gacgtcagcc acggcctgat gatgagtgaa gccgagcaat tgaataaagg ctttctcaag
0421 cggatgcgca ccggctttcc ttatattcag ttaaaacttg gcgcatcgct tgatggtcgc acggcgatgg
0491 cgagcggcga aagccagtgg atcacttcgc cccaggcgcg gcgtgatgta caactactgc gcgcgcaaag
0561 tcatgccatt ttaaccagca gcgccacggt gctggcggat gatcctgcct taacggtgcg ttggtctgaa
0631 ctggatgaac aaactcaggc gctctatccg caacaaaatc tccgtcagcc gatacgtatt gtgattgata
0701 gccaaaatcg cgtgacgccg gtacatcgca ttgtgcagca gcccggcgaa acctggttcg cgcgtacgca
0771 ggaagattct cgtgagtggc cggaaacggt gcgtaccttg ctgattccag agcataaagg tcatctggat
0841 ctggttgtac tgatgatgca actgggtaaa cagcaaatta acagcatctg ggtggaagcg gggccaacgc
0911 tcgctggcgc attgctgcag gcgggtttag tcgatgagct gattgtctat atcgcaccta aactattagg
0981 cagcgacgcc cgcggattat gcacgctgcc agggcttgag aaattagccg acgcccccca atttaaattc
1051 aaagagatac gtcatgtagg cccggatgtt tgcctgcatt tagtgggtgc atgaTCTCCC GGCTCGAAAG
1121 GGAAGCAGCG CACGAAATAT TATGCTAAAA TCCGCCCCCC TGCGGGGCCA TACTCGAACC CGAAGGAAGA
1191 AAATGAACAT TATT
|