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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCR30
(D)
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|
Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
leuO
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Related strains
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Strains Search
|
Search strains by gene name:
leuO
Search strains by all related name:
leuO b0076 ECK0078 JW0075
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General information (Go to Linear View: )
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Gene Name
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leuO
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Alternative name
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b0076,ECK0078,JW0075
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Location, Length
|
84,368 - 85,312
(
+
)
;
1.82
min
;
945
(bp) ,
314
(aa)
|
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Product
|
DNA-binding transcriptional activator
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Operon Name
|
leuO
|
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Note
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probable transcriptional activator for leuABCD operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0009098 - leucine biosynthetic process; GO_process: GO:0006350 - transcription
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Function
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putative regulator; Amino acid biosynthesis: Leucine
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Gene Ontology
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GO:0003677
;
DNA binding ( leuO )
GO:0003700
;
transcription factor activity ( leuO )
GO:0006350
;
transcription ( leuO )
GO:0006355
;
regulation of transcription, DNA-dependent ( leuO )
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PID
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87081684
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
|
LEUO_ECOLI
(
P10151
;
P75640
)
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- Protein name
|
Probable HTH-type transcriptional regulator leuO.
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- Synonyms
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- Gene name
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Name=leuO; OrderedLocusNames=b0076;
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MMBR References
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Mol Microbiol. 1997;25(3):559-69.
The LysR-like regulator LeuO in Escherichia coli is involved in the translational regulation of rpoS by affecting the expression of the small regulatory DsrA-RNA.
Klauck E, Bohringer J, Hengge-Aronis R.
(
9302018
)
|
J Bacteriol. 1995;177:810-814
Effects of multicopy LeuO on the expression of the acid-inducible lysine decarboxylase gene in Escherichia coli.
Shi, X., and G. N. Bennett.
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J Bacteriol. 1998;180:190-193
The leuO gene product has a latent ability to relieve bgl silencing in Escherichia coli.
Ueguchi, C., T. Ohta, C. Seto, T. Suzuki, and T. Mizuno.
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| Sequences |
Amino acid
FASTA format
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0001 MPEVQTDHPE TAELSKPQLR MVDLNLLTVF DAVMQEQNIT RAAHVLGMSQ PAVSNAVARL KVMFNDELFV
0071 RYGRGIQPTA RAFQLFGSVR QALQLVQNEL PGSGFEPASS ERVFHLCVCS PLDSILTSQI YNHIEQIAPN
0141 IHVMFKSSLN QNTEHQLRYQ ETEFVISYED FHRPEFTSVP LFKDEMVLVA SKNHPTIKGP LLKHDVYNEQ
0211 HAAVSLDRFA SFSQPWYDTV DKQASIAYQG MAMMSVLSVV SQTHLVAIAP RWLAEEFAES LELQVLPLPL
0281 KQNSRTCYLS WHEAAGRDKG HQWMEEQLVS ICKR
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CTTTTTCTTA TTTTATATGC ATGATAAATC
-070 ATATTCTTCA GGATTATTTC TCTGCATTCC AATAAGGGAA AGGGAGTTAA GTGTGACAGT GGAGTTAAGT
0001 atgccagagg tacaaacaga tcatccagag acggcggagt taagcaaacc acagctacgc atggtcgatc
0071 tcaacttatt aaccgttttc gatgccgtga tgcaggagca aaacattact cgtgccgctc atgttctggg
0141 aatgtcgcaa cctgcggtca gtaacgctgt tgcacgcctg aaggtgatgt ttaatgacga gctttttgtt
0211 cgttatggcc gtggtattca accgactgct cgcgcatttc aactttttgg ttcagttcgt caggcattgc
0281 aactagtaca aaatgaattg cctggttcag gttttgaacc cgcgagcagt gaacgtgtat ttcatctttg
0351 tgtttgcagc ccgttagaca gcattctgac ctcgcagatt tataatcaca ttgagcagat tgcgccaaat
0421 atacatgtta tgttcaagtc ttcattaaat cagaacactg aacatcagct gcgttatcag gaaacggagt
0491 ttgtgattag ttatgaagac ttccatcgtc ctgaatttac cagcgtacca ttatttaaag atgaaatggt
0561 gctggtagcc agcaaaaatc atccaacaat taagggcccg ttactgaaac atgatgttta taacgaacaa
0631 catgcggcgg tttcgctcga tcgtttcgcg tcatttagtc aaccttggta tgacacggta gataagcaag
0701 ccagtatcgc gtatcagggc atggcaatga tgagcgtact tagcgtggtg tcgcaaacgc atttggtcgc
0771 tattgcgccg cgttggctgg ctgaagagtt cgctgaatcc ttagaattac aggtattacc gctgccgtta
0841 aaacaaaaca gcagaacctg ttatctctcc tggcatgaag ctgccgggcg cgataaaggc catcagtgga
0911 tggaagagca attagtctca atttgcaaac gctaaCTGAT TGCAGAATAG GTCAGACATG AATGTCTGGT
0981 TTATTCTGCA TTTTTTATTG AATGTAGAAT TTTATTCTGA ATGTGTGGGC TCTCTATTTT AGGAT
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