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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCR30
(D)
,
OCR30,31-3 (BK2-1 / AK1-1)
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
cra
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Related strains
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Strains Search
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Search strains by gene name:
cra
Search strains by all related name:
cra b0080 cra ECK0081 fruC fruR fruS? JW0078 serR? shl
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General information (Go to Linear View: )
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Gene Name
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cra
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Alternative name
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b0080,cra,ECK0081,fruC,fruR,fruS?,JW0078,serR?,shl
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Location, Length
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88,028 - 89,032
(
+
)
;
1.90
min
;
1005
(bp) ,
334
(aa)
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Product
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DNA-binding transcriptional repressor-activator for carbon metabolism
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Operon Name
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fruR
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Note
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transcriptional repressor of fru operon and others; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0006096 - glycolysis; GO_process: GO:0006350 - transcription
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Function
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regulator; Energy metabolism, carbon: Glycolysis
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Gene Ontology
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GO:0003677
;
DNA binding ( fruR )
GO:0003700
;
transcription factor activity ( fruR )
GO:0005622
;
intracellular ( fruR )
GO:0006350
;
transcription ( fruR )
GO:0006355
;
regulation of transcription, DNA-dependent ( fruR )
GO:0009750
;
response to fructose stimulus ( fruR )
GO:0045449
;
regulation of transcription ( fruR )
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PID
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1786268
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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FRUR_ECOLI
(
P21168
)
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- Protein name
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Fructose repressor
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- Synonyms
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Catabolite repressor/activator
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- Gene name
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OrderedLocusNames=b0080, c0098, z0090, ECs0084, SF0075, S0077;
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MMBR References
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Mol Gen Genet. 1986;203(3):435-44.
Relationship between pseudo-HPr and the PEP: fructose phosphotransferase system in Salmonella typhimurium and Escherichia coli.
Geerse RH, Ruig CR, Schuitema AR, Postma PW.
(
3528748
)
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Mol Gen Genet. 1991;226(1-2):332-6.
Nucleotide sequence of the ilvH-fruR gene region of Escherichia coli K12 and Salmonella typhimurium LT2.
Jahreis K, Postma PW, Lengeler JW.
(
1851954
)
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J Gen Microbiol. 1987;133(2):341-6.
Location and function of fruC, a gene involved in the regulation of fructose utilization by Escherichia coli.
Kornberg HL, Elvin CM.
(
3309151
)
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Curr Microbiol. 1996;33(4):270-4.
Cooperative interaction between Cra and Fnr in the regulation of the cydAB operon of Escherichia coli.
Ramseier TM, Chien SY, Saier MH Jr.
(
8824175
)
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FEMS Microbiol Lett. 1996;138(2-3):97-103.
Cyclic AMP-independent catabolite repression in bacteria.
Saier MH Jr.
(
9026456
)
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J Bacteriol. 1996;178:280-283
FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli.
Bledig, S. A., T. M. Ramseier, and M. H. Saier, Jr.
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| Sequences |
Amino acid
FASTA format
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0001 MKLDEIARLA GVSRTTASYV INGKAKQYRV SDKTVEKVMA VVREHNYHPN AVAAGLRAGR TRSIGLVIPD
0071 LENTSYTRIA NYLERQARQR GYQLLIACSE DQPDNEMRCI EHLLQRQVDA IIVSTSLPPE HPFYQRWAND
0141 PFPIVALDRA LDREHFTSVV GADQDDAEML AEELRKFPAE TVLYLGALPE LSVSFLREQG FRTAWKDDPR
0211 EVHFLYANSY EREAAAQLFE KWLETHPMPQ ALFTTSFALL QGVMDVTLRR DGKLPSDLAI ATFGDNELLD
0281 FLQCPVLAVA QRHRDVAERV LEIVLASLDE PRKPKPGLTR IKRNLYRRGV LSRS
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Nucleotide
FASTA format
View sequence out neighbor 100bp
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-100 AAGCAGTTGC CGCAGTTAAT TTTCTGCGCT
-070 TAGATGTTAA TGAATTTAAC CCATACCAGT ACAATGGCTA TGGTTTTTAC ATTTTACGCA AGGGGCAATT
0001 gtgaaactgg atgaaatcgc tcggctggcg ggagtgtcgc ggaccactgc aagctatgtt attaacggca
0071 aagcgaagca ataccgtgtg agcgacaaaa ccgttgaaaa agtcatggct gtggtgcgtg agcacaatta
0141 ccacccgaac gccgtggcag ctgggcttcg tgctggacgc acacgttcta ttggtcttgt gatccccgat
0211 ctggagaaca ccagctatac ccgcatcgct aactatcttg aacgccaggc gcggcaacgg ggttatcaac
0281 tgctgattgc ctgctcagaa gatcagccag acaacgaaat gcggtgcatt gagcaccttt tacagcgtca
0351 ggttgatgcc attattgttt cgacgtcgtt gcctcctgag catccttttt atcaacgctg ggctaacgac
0421 ccgttcccga ttgtcgcgct ggaccgcgcc ctcgatcgtg aacacttcac cagcgtggtt ggtgccgatc
0491 aggatgatgc cgaaatgctg gcggaagagt tacgtaagtt tcccgccgag acggtgcttt atcttggtgc
0561 gctaccggag ctttctgtca gcttcctgcg tgaacaaggt ttccgtactg cctggaaaga tgatccgcgc
0631 gaagtgcatt tcctgtatgc caacagctat gagcgggagg cggctgccca gttattcgaa aaatggctgg
0701 aaacgcatcc gatgccgcag gcgctgttca caacgtcgtt tgcgttgttg caaggagtga tggatgtcac
0771 gctgcgtcgc gacggcaaac tgccttctga cctggcaatt gccacctttg gcgataacga actgctcgac
0841 ttcttacagt gtccggtgct ggcagtggct caacgtcacc gcgatgtcgc agagcgtgtg ctggagattg
0911 tcctggcaag cctggacgaa ccgcgtaagc caaaacctgg tttaacgcgc attaaacgta atctctatcg
0981 ccgcggcgtg ctcagccgta gctaaGCCGC GAACAAAAAT ACGCGCCAGG TGAATTTCCC TCTGGCGCGT
1051 AGAGTACGGG ACTGGACATC AATATGCTTA AAGTAAATAA GACTATTCCT GACTA
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