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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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J Biol Chem. 1996;271(44):27795-801.
Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis.
Heath RJ, Rock CO.
(
8910376
)
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Deletion
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OCR33,35-4 (AK4-2 / BK5-2)
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
fabZ
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Related strains
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Strains Search
|
Search strains by gene name:
fabZ
Search strains by all related name:
fabZ b0180 ECK0179 JW0175 sabA sefA sfhC yaeA
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General information (Go to Linear View: )
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Gene Name
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fabZ
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Alternative name
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b0180,ECK0179,JW0175,sabA,sefA,sfhC,yaeA
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Location, Length
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202,101 - 202,556
(
+
)
;
4.36
min
;
456
(bp) ,
151
(aa)
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Product
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(3R)-hydroxymyristol acyl carrier protein dehydratase
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Operon Name
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bamA-hlpA-lpxD-fabZ-lpxAB-rnhB-dnaE
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Note
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GO_component: GO:0005737 - cytoplasm
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Function
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enzyme; Fatty acid and phosphatidic acid biosynthesis
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Gene Ontology
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GO:0005737
;
cytoplasm ( fabZ )
GO:0006633
;
fatty acid biosynthetic process ( fabZ )
GO:0008610
;
lipid biosynthetic process ( fabZ )
GO:0009245
;
lipid A biosynthetic process ( fabZ )
GO:0016829
;
lyase activity ( fabZ )
GO:0016836
;
hydro-lyase activity ( fabZ )
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PID
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1786377
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EC number
(KEGG Pathway)
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4.2.1.-
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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fabZ
(
EG11284
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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FABZ_ECOLI
(
P21774
)
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- Protein name
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(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase
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- Synonyms
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EC 4.2.1.-) ((3R)-hydroxymyristoyl ACP dehydrase, 17 kDa actomyosin component
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- Gene name
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OrderedLocusNames=b0180, c0217, z0192, ECs0182, SF0170, S0173;
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MMBR References
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J Biol Chem. 1994;269:32896-32903
An Escherichia coli gene (fabZ) encoding (3R)-hydroxymyristoyl acyl carrier protein dehydrase.
Mohan, S., T. M. Kelly, S. S. Eveland, C. R. H. Raetz, and M. S. Anderson.
|
J Bacteriol. 1976;128(1):401-12.
Septum formation-defective mutant of Escherichia coli.
Normark S, Norlander L, Grundstrom T, Bloom GD, Boquet P, Frelat G.
(
789345
)
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| Sequences |
Amino acid
FASTA format
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0001 MTTNTHTLQI EEILELLPHR FPFLLVDRVL DFEEGRFLRA VKNVSVNEPF FQGHFPGKPI FPGVLILEAM
0071 AQATGILAFK SVGKLEPGEL YYFAGIDEAR FKRPVVPGDQ MIMEVTFEKT RRGLTRFKGV ALVDGKVVCE
0141 ATMMCARSRE A
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 CCATCTTTTG TTCGCCAAAC TTTACGGCCT
-070 GTCTCATTCT TACGATTGCG GCAGGCCGTG TTATTATTGT CGTTTCTTAT ATTTTGACAG GAAGAGTATC
0001 ttgactacta acactcatac tctgcagatt gaagagattt tagaacttct gccgcaccgt ttcccgttct
0071 tactggtgga tcgcgtgctg gattttgaag aaggtcgttt tctgcgcgca gtaaaaaatg tctctgtcaa
0141 tgagccattc ttccagggcc atttccctgg aaaaccgatt ttcccgggtg tgctgattct ggaagcaatg
0211 gcacaggcaa caggtattct ggcgtttaaa agcgtaggaa aactggaacc gggtgagctg tactacttcg
0281 ctggtattga cgaagcgcgc ttcaagcgcc cggtcgtgcc tggcgatcaa atgatcatgg aagtcacttt
0351 cgaaaaaacg cgccgcggcc tgacccgttt taaaggggtt gctctggtcg atggtaaagt agtttgcgaa
0421 gcaacgatga tgtgtgctcg tagccgggag gcctgaTACG TGATTGATAA ATCCGCCTTT GTGCATCCAA
0491 CCGCCATTGT GGAAGAGGGC GCGTCAATTG GCGCGAACGC ACACATTGGT CCTTTTTGTA TCGTTG
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