|
PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
OCR32
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
dksA
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
dksA
Search strains by all related name:
dksA b0145 ECK0144 JW0141 msmA
|
General information (Go to Linear View: )
|
|
Gene Name
|
dksA
|
|
Alternative name
|
b0145,ECK0144,JW0141,msmA
|
|
Location, Length
|
160,149 - 160,604
(
-
)
;
3.45
min
;
456
(bp) ,
151
(aa)
|
|
Product
|
DNA-binding transcriptional regulator of rRNA transcription, DnaK suppressor protein
|
|
Operon Name
|
sfsA-dksA-yadB
|
|
Note
|
dnaK suppressor protein; GO_component: GO:0005737 - cytoplasm; GO_process: GO:0006457 - protein folding
|
|
Function
|
phenotype; DNA - replication, repair,restriction/modification
|
|
Gene Ontology
|
GO:0005737
;
cytoplasm ( dksA )
GO:0008270
;
zinc ion binding ( dksA )
GO:0046872
;
metal ion binding ( dksA )
|
|
PID
|
1786338
|
EC number
(KEGG Pathway)
|
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
dksA
(
EG10230
)
|
|
Number of removed
|
0 aa cleaved
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
DKSA_ECOLI
(
P18274
)
|
|
- Protein name
|
DnaK suppressor protein.
|
|
- Synonyms
|
|
|
- Gene name
|
OrderedLocusNames=b0145, c0178, z0156, ECs0149, SF0137, S0140;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
dksA
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Crystal Structure Of Transcription Factor Dksa From E. Coli
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
DnaK suppressor protein
|
|
PSI-BLAST
|
DnaK suppressor protein
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
dnaK suppressor
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
CAMP_PHOSPHO_SITE
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
DKSA_TRAR_ZN_FINGER
|
|
MMBR References
|
J Bacteriol. 1990;172(4):2055-64.
Identification and characterization of a new Escherichia coli gene that is a dosage-dependent suppressor of a dnaK deletion mutation.
Kang PJ, Craig EA.
(
2180916
)
|
Mol Microbiol. 1994;13(2):301-12.
Cloning, sequencing, and characterization of multicopy suppressors of a mukB mutation in Escherichia coli.
Yamanaka K, Mitani T, Ogura T, Niki H, Hiraga S.
(
7984109
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MQEGQNRKTS SLSILAIAGV EPYQEKPGEE YMNEAQLAHF RRILEAWRNQ LRDEVDRTVT HMQDEAANFP
0071 DPVDRAAQEE EFSLELRNRD RERKLIKKIE KTLKKVEDED FGYCESCGVE IGIRRLEARP TADLCIDCKT
0141 LAEIREKQMA G
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 cgtttagata attgctatcc ggaaaagcat
-070 ctgctattta tagcggcctc atttttcccc cgaacatggg gatcgatagt gcgtgttaag gagaagcaac
0001 atgcaagaag ggcaaaaccg taaaacatcg tccctgagta ttctcgccat cgctggggtg gaaccatatc
0071 aggagaagcc gggcgaagag tatatgaatg aagcccagct ggcgcacttc cgtcgtattc tggaagcatg
0141 gcgtaatcaa ctcagggatg aagtcgatcg caccgttaca catatgcagg atgaagcagc caacttcccg
0211 gacccggtag accgtgcagc ccaggaagaa gagttcagcc tcgaactgcg taaccgcgat cgcgagcgta
0281 agctgatcaa aaagatcgag aagacgctga aaaaagtgga agacgaagat ttcggctact gcgaatcctg
0351 cggtgttgaa attggtattc gccgtctgga agcgcgcccg acagccgatc tgtgcatcga ctgcaaaacg
0421 ctggctgaaa ttcgcgaaaa acagatggct ggctaattac agccgttcca tcacgtttac cacaggcggg
0491 aaatgctccc gccttatttt ttgttcaaag agatgacaga cacacagtat attggccgct tcgccc
|
