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PEC Original Annotations
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Essentiality
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Class
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essential
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References (PMID)
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Mol Gen Genet. 1991;227(1):49-51.
Development of stable, genetically well-defined conditionally viable Escherichia coli strains.
Degryse E.
(
1646386
)
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Deletion
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OCR33,35-4 (AK4-2 / BK5-2)
(D)
,
OCR33-16
(D)
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Related gene (W3110 PEC)
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Gene Search
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Search MG1655 PEC by gene name:
dapD
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Related strains
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Strains Search
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Search strains by gene name:
dapD
Search strains by all related name:
dapD b0166 ECK0164 JW0161 ssa
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General information (Go to Linear View: )
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Gene Name
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dapD
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Alternative name
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b0166,ECK0164,JW0161,ssa
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Location, Length
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185,123 - 185,947
(
-
)
;
3.99
min
;
825
(bp) ,
274
(aa)
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Product
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2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase
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Operon Name
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map-glnD-dapD
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Note
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GO_component: GO:0005737 - cytoplasm; GO_process: GO:0009089 - lysine biosynthetic process via diaminopimelate
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Function
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enzyme; Amino acid biosynthesis: Lysine
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Gene Ontology
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GO:0005737
;
cytoplasm ( dapD )
GO:0008415
;
acyltransferase activity ( dapD )
GO:0008652
;
amino acid biosynthetic process ( dapD )
GO:0008666
;
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity ( dapD )
GO:0009085
;
lysine biosynthetic process ( dapD )
GO:0009089
;
lysine biosynthetic process via diaminopimelate ( dapD )
GO:0016740
;
transferase activity ( dapD )
GO:0016757
;
transferase activity, transferring glycosyl groups ( dapD )
GO:0019877
;
diaminopimelate biosynthetic process ( dapD )
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PID
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1786362
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EC number
(KEGG Pathway)
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2.3.1.117
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
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EcoGene
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dapD
(
EG10207
)
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Number of removed
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0 aa cleaved
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SWISS-PROT
(
Show details
[
2
more]
)
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Entry name(Acc.no)
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DAPD_ECOLI
(
P03948
)
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- Protein name
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2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
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- Synonyms
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EC 2.3.1.117, Tetrahydrodipicolinate N-succinyltransferase, THP succinyltransferase, Tetrahydropicolinate succinylase
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- Gene name
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Name=dapD; OrderedLocusNames=b0166, SF0156, S0159;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
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dapD
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
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PSI-BLAST
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Chain , Complex Of Tetrahydrodipicolinate N-Succinyltransferase With 2-Amino-6-Oxopimelate And Coenzyme A
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SWISS-PROT
(database updated :
2007.02.20
)
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BLAST
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2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase (Tetrahydrodipicolinate N-succinyltransferase) (THP succinyltransferase) (Tetrahydropicolinate succinylase)
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PSI-BLAST
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2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase
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nr
(database updated :
2007.02.20
)
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BLAST
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2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
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PROSITE
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PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
HEXAPEP_TRANSFERASES
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MMBR References
|
Mol Gen Genet. 1991;227(1):49-51.
Development of stable, genetically well-defined conditionally viable Escherichia coli strains.
Degryse E.
(
1646386
)
|
Arch Biochem Biophys. 1980;203(1):181-9.
Glutamine synthetase cascade: enrichment of uridylyltransferase in Escherichia coli carrying hybrid ColE1 plasmids.
Garcia E, Federici M, Rhee SG, Berberich MA.
(
6105849
)
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Mol Gen Genet. 1981;181(3):356-62.
Organization of genes in the four minute region of the Escherichia coli chromosome: evidence that rpsB and tsf are co-transcribed.
Bendiak DS, Friesen JD.
(
7017348
)
|
J Biol Chem. 1984;259:14824-14828
Regulation of expression and nucleotide sequence of the Escherichia coli dapD gene.
Richaud, C., F. Richaud, C. Martin, C. Haziza, and J. C. Patte.
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| Sequences |
Amino acid
FASTA format
|
0001 MQQLQNIIET AFERRAEITP ANADTVTREA VNQVIALLDS GALRVAEKID GQWVTHQWLK KAVLLSFRIN
0071 DNQVIEGAES RYFDKVPMKF ADYDEARFQK EGFRVVPPAA VRQGAFIARN TVLMPSYVNI GAYVDEGTMV
0141 DTWATVGSCA QIGKNVHLSG GVGIGGVLEP LQANPTIIED NCFIGARSEV VEGVIVEEGS VISMGVYIGQ
0211 STRIYDRETG EIHYGRVPAG SVVVSGNLPS KDGKYSLYCA VIVKKVDAKT RGKVGINELL RTID
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 taataacgag ttgcagcagg aagtgcatca
-070 gcggttgaca gaggccctca atccaaacga taaagggtga tgtgtttact gatatgaaaa gagtttaaca
0001 atgcagcagt tacagaacat tattgaaacc gcttttgaac gccgtgccga gatcacgcca gccaatgcag
0071 acaccgttac ccgcgaagcg gtaaatcagg tgatcgccct gctggattcc ggcgcactgc gtgtagcgga
0141 aaaaattgac ggtcagtggg tgacgcatca gtggttgaaa aaagcggtgc tgctctcttt ccgtattaat
0211 gataatcagg tgatcgaagg ggcagaaagc cgctacttcg acaaagtgcc gatgaaattc gccgactacg
0281 acgaagcacg tttccagaaa gaaggcttcc gcgttgtgcc accagcggcg gtacgtcagg gtgcgtttat
0351 tgcccgtaac accgtgctga tgccgtctta cgtcaacatc ggcgcatatg ttgatgaagg caccatggtt
0421 gatacctggg cgaccgtcgg ttcttgtgcg cagattggta aaaacgtcca cctttccggt ggcgtgggca
0491 tcggcggcgt gctggaaccg ctgcaggcta acccaaccat cattgaagat aattgcttca tcggcgcgcg
0561 ctctgaagtg gttgaagggg tgattgtcga agaaggttcc gtcatttcca tgggcgtata cattggtcag
0631 agcacccgta tttacgaccg tgaaaccggc gaaatccact acggtcgcgt tccggcgggg tctgtggttg
0701 tttcaggtaa tctgccgtca aaagatggca aatacagcct ctactgtgcg gttatcgtta agaaagttga
0771 cgcgaaaact cgcggcaaag tcggcattaa cgaactgctg cgtaccatcg actaaaagta tgcacacggg
0841 cagcacgacg ctgcccgatt tttttgcagg gatgagcgat gatttcacgc cgccgatttt tgcaggctac
0911 tgccgcgacg atagc
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