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PEC Original Annotations
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|
Essentiality
|
|
Class
|
non-essential
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|
References (PMID)
|
J Gen Microbiol. 1977;99(2):263-76.
Biochemical genetics of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: isolation and biochemical properties of deletion mutants.
Langley D, Guest JR.
(
327021
)
|
|
|
Deletion
|
DE(nadC-aceF)72
,
OCR31
(D)
,
OCR31-7
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
aroP
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
aroP
Search strains by all related name:
aroP b0112 ECK0111 JW0108
|
General information (Go to Linear View: )
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Gene Name
|
aroP
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|
Alternative name
|
b0112,ECK0111,JW0108
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|
Location, Length
|
120,178 - 121,551
(
-
)
;
2.59
min
;
1374
(bp) ,
457
(aa)
|
|
Product
|
aromatic amino acid transporter
|
|
Operon Name
|
aroP
|
|
Note
|
aromatic amino acid transport protein; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009094 - L-phenylalanine biosynthetic process; GO_process: GO:0006571 - tyrosine biosynthetic process
|
|
Function
|
transport; Transport of small molecules: Amino acids, amines
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( aroP )
GO:0006810
;
transport ( aroP )
GO:0006865
;
amino acid transport ( aroP )
GO:0015171
;
amino acid transmembrane transporter activity ( aroP )
GO:0016020
;
membrane ( aroP )
GO:0016021
;
integral to membrane ( aroP )
|
|
PID
|
1786302
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
AROP_ECOLI
(
P15993
;
P75650
)
|
|
- Protein name
|
Aromatic amino acid transport protein aroP
|
|
- Synonyms
|
General aromatic amino acid permease
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- Gene name
|
Name=aroP; OrderedLocusNames=b0112;
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Homology Analysis
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BLAST
|
|
Bacteria
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GTOP
|
aroP
(
homologous genes of other bacterias
)
|
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PDB
(database updated :
2007.02.20
)
|
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PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
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BLAST
|
Aromatic amino acid transport protein aroP
|
|
PSI-BLAST
|
High-affinity glutamine permease
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
aromatic amino acid transporter [Escherichia coli K12]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
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Pfam
|
|
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
AMINO_ACID_PERMEASE
|
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MMBR References
|
J Gen Microbiol. 1980;121(2):277-92.
Molecular cloning of the pyruvate dehydrogenase complex genes of Escherichia coli.
Guest JR, Stephens PE.
(
6455499
)
|
J Gen Microbiol. 1983;129(3):671-80.
Hybrid plasmids containing the pyruvate dehydrogenase complex genes and gene-DNA relationships in the 2 to 3 minute region of the Escherichia coli chromosome.
Guest JR, Roberts RE, Stephens PE.
(
6308128
)
|
J Gen Microbiol. 1981;127:65-79.
Organization and expression of the pyruvate dehydrogenase complex genes of Escherichia coli K12.
Guest, J. R., S. T. Cole, and K. Jeyaseelan.
|
J Bacteriol. 1975;122(3):957-65.
Transport of L-4-azaleucine in Escherichia coli.
Harrison LI, Christensen HN, Handlogten ME, Oxender DL, Quay SC.
(
238951
)
|
Nucleic Acids Res. 1990;18(3):653
Nucleotide sequence of the aroP gene encoding the general aromatic amino acid transport protein of Escherichia coli K-12: homology with yeast transport proteins.
Honore N, Cole ST.
(
2408019
)
|
J Bacteriol. 1959;78:511-9.
Action of azaserine on Escherichia coli.
Kaplan L, Reilly HC, Stuck CC.
(
14404400
)
|
J Gen Microbiol. 1977;99(2):263-76.
Biochemical genetics of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: isolation and biochemical properties of deletion mutants.
Langley D, Guest JR.
(
327021
)
|
J Gen Microbiol. 1978;106(1):103-17.
Biochemical genetics of the alpha-keto acid dehydrogenase complexes of Escherichia coli K12: genetic characterization and regulatory properties of deletion mutants.
Langley D, Guest JR.
(
349114
)
|
J Bacteriol. 1988;170(1):463-7.
Genetic and molecular characterization of the guaC-nadC-aroP region of Escherichia coli K-12.
Roberts RE, Lienhard CI, Gaines CG, Smith JM, Guest JR.
(
3275629
)
|
J Bacteriol. 1970;104(1):177-88.
Formation of aromatic amino acid pools in Escherichia coli K-12.
Brown KD.
(
4919744
)
|
J Bacteriol. 1987;169(1):386-93.
Transcription control of the aroP gene in Escherichia coli K-12: analysis of operator mutants.
Chye ML, Pittard J.
(
3025182
)
|
J Bacteriol. 1986;167(2):749-53.
Cloning of the aroP gene and identification of its product in Escherichia coli K-12.
Chye ML, Guest JR, Pittard J.
(
3015892
)
|
Arch Biochem Biophys. 1964;104:1-18.
Uptake of amino acids by Salmonella typhimurium.
Ames GF-L.
(
14110716
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MMEGQQHGEQ LKRGLKNRHI QLIALGGAIG TGLFLGSASV IQSAGPGIIL GYAIAGFIAF LIMRQLGEMV
0071 VEEPVAGSFS HFAYKYWGSF AGFASGWNYW VLYVLVAMAE LTAVGKYIQF WYPEIPTWVS AAVFFVVINA
0141 INLTNVKVFG EMEFWFAIIK VIAVVAMIIF GGWLLFSGNG GPQATVSNLW DQGGFLPHGF TGLVMMMAII
0211 MFSFGGLELV GITAAEADNP EQSIPKATNQ VIYRILIFYI GSLAVLLSLM PWTRVTADTS PFVLIFHELG
0281 DTFVANALNI VVLTAALSVY NSCVYCNSRM LFGLAQQGNA PKALASVDKR GVPVNTILVS ALVTALCVLI
0351 NYLAPESAFG LLMALVVSAL VINWAMISLA HMKFRRAKQE QGVVTRFPAL LYPLGNWICL LFMAAVLVIM
0421 LMTPGMAISV YLIPVWLIVL GIGYLFKEKT AKAVKAH
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 aaacttcttt gatgtaaaca aattaataca
-070 acaaacggaa ttgcaaactt acacacgcat cactgcgtag atcaaaaaaa caaccaccgc acgaggtttc
0001 atgatggaag gtcaacagca cggcgagcag ctaaagcgcg gccttaaaaa ccgccatatt cagcttatcg
0071 cgctgggtgg cgcgataggg accgggttat tcctgggtag cgcctccgta atacagtccg cagggccagg
0141 gattatcctg ggttacgcca ttgctggttt tatcgccttt ctgatcatgc gtcagctggg tgaaatggtg
0211 gtcgaagaac ctgtcgcagg ctcctttagc cactttgctt ataaatactg gggcagtttt gccggtttcg
0281 cctctggctg gaactactgg gtactgtacg ttttagttgc catggctgag ctgactgccg tgggtaaata
0351 cattcagttc tggtatccgg aaatccccac ctgggtttct gccgccgtat tctttgtggt gattaacgcc
0421 atcaacctga ccaacgttaa agtgtttggc gagatggagt tctggtttgc cattatcaaa gttatcgcgg
0491 tggtagcgat gatcatcttc ggcggctggc tgctattcag tggcaacggc ggcccgcagg cgaccgttag
0561 caacctgtgg gatcagggtg gtttcctgcc gcacggcttc accgggctgg tgatgatgat ggcgattatc
0631 atgttctcgt tcggtggtct ggaactggtg gggatcaccg cagcagaagc tgataacccg gagcaaagta
0701 taccgaaagc aactaaccag gttatctacc gcatcctgat tttctatatt ggttcgttag ccgttctgct
0771 ctcactgatg ccgtggaccc gcgttaccgc cgataccagt ccgtttgtgc tgatcttcca cgagttaggc
0841 gatacctttg tggcgaatgc gctgaacatc gtggtactga ctgcggcgct ctccgtgtac aacagctgcg
0911 tatattgcaa cagccgtatg ctgtttggtc tggcacaaca gggtaatgcg ccaaaagcgc tggcgtctgt
0981 cgataaacgt ggtgtaccag taaataccat tctggtgtct gcactggtaa cggcgttgtg cgtactgatt
1051 aactaccttg ccccagagtc cgctttcgga ctgttaatgg cgctggtggt atctgcactg gtaatcaact
1121 gggcgatgat tagcctggcg catatgaaat tccgtcgcgc caagcaggaa caaggcgtgg taactcgctt
1191 ccctgctctg ctttatccgc tgggtaactg gatctgcctg ctgtttatgg cggcggtact ggtgattatg
1261 ctgatgaccc caggaatggc gatttcggta tacctgatcc cggtatggct gatcgtgtta ggtatcggct
1331 atctgtttaa agagaaaacc gccaaagccg taaaagcgca ttaatctctc tacgccctca cccgtacagg
1401 gtgagggcaa taatctttac accaacgccc cgtaaatcgt cagtagtgca atcaccacca cgaccacgaa
1471 cgag
|
